DIAL provides access to three alignment algorithms: global (Needleman-Wunsch), local (Smith-Waterman) and global-semiglobal (motif search). Given a query structural motif, the latter algorithm may be used to detect structurally similar regions in the target structure. The DIAL web server provides graphical output which allows the user to view and rotate the 3-dimensional superposition for the optimal alignment of query to target. Although graphical output is available for all three algorithms, the global-semiglobal motif search may be of most interest in attempts to identify RNA motifs.
If you use the DIAL web server for your work, please cite the following reference.
DIAL: A web server for RNA structural alignment using dihedral anglesPython programs designed by P. Clote and F. Ferre, implemented by F. Ferre, W.A. Lorenz and Y. Ponty. Web server developed by V. Chistyakov, F. Ferre, Y. Ponty, J. Persampieri.
F. Ferre, W.A. Lorenz, Y. Ponty, P. Clote
This material is based upon work supported by the National Science Foundation under Grant No. 0543506. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation.