Main Page - The MarthLab

From The MarthLab

[edit] Postdoctoral opportunities

As of September 2008 several postdoc positions are available for next-generation software development and data mining.

[edit] Graduate studies in the laboratory

We are looking for graduate students who wish to work towards a Ph.D. in computational genomics.

[edit] Welcome!

Thank you for visiting the home page of the Computational Biology Laboratory of Gabor T.Marth in the Department of Biology at Boston College. The lab is housed in Higgins Hall on the Chestnut Hill Campus of Boston College. For our main Bioinformatics / Computational Biology portal, please visit: http://bioinformatics.bc.edu .

[edit] Mission

Genetic and epigenetic variations (or polymorphisms) are important, often heritable landmarks of a species' genome and many of them cause phenotypic differences. Such inherited or somatic polymorphisms in the human genome can lead to hereditary diseases. Read more...

[edit] Projects

Our current focus is on the development of resequencing software for the analysis of vast amounts of next-generation sequencer data. We are also developing sequencing informatics methods for emerging applications of next-generation sequencers. We have applied our tools in specific data mining projects, for the discovery or SNPs and short INDELs in Illumina (Solexa) and 454 resequencing reads. The lab also works on population genetic theory and modeling techniques. Our future plans include the development of cancer genetic analysis tools.

[edit] Software for whole-genome re-sequencing

We also include a link to our original SNP discovery program:

PolyBayes: Polymorphism Discovery in Capillary Sequences

PyroBayes, Mosaik, EagleView, and GigaBayes are now in beta release. If you are interested in acquiring / testing our software or learn more about how they work together please visit the beta release page.