From The MarthLab
Originally from Stockholm, Sweden; Michael decided to pursue a doctorate in bioinformatics after having been a systems architect and consultant for many years. He has been active within the computer security & forensics, advanced media technology, supercomputing, systems administration, military communications, as well as financial and mobile communications fields.
Before arriving at Boston College, he was working on a pilot project at the Karolinska Institute (the institution that awards the Nobel prizes in chemistry and medicine) that tried to create a signal pathway simulation of any arbitrary cell. Templates based on microarray data were used to set the simulation conditions and the signal pathways themselves were harvested from medline articles using automated techniques.
Now he's happily working in the Marth lab in the joint bionformatics room. Just look for the giant Toblerone box and the Swedish pennant flag.
Contents |
[edit] Current Projects
- Mosaik: The Next-Generation Reference Guided Assembler
- SimSolexa: An Illumina (Solexa) synthetic data set creation tool using the empirical error profile from Solexa reads while simulating SNPs and sequencing errors.
- Assembly-based indel detection
- Somatic mutation detection using healthy and diseased tissue samples
- Polymorphism detection for the Illumina (formerly Solexa) platform
- De novo repeat finding and genome resequenceability assessement
[edit] Education
Royal Institute of Technology (KTH), Stockholm, Sweden.
Master's degree in computer engineering with a specialization in biomedical engineering
Heavy emphasis on bioinformatics and neural network research
Master's thesis: Improving SNP Discovery Performance Using Advanced Algorithms
University of Florida, Gainesville, Florida.
Undergraduate studies in computer engineering and Japanese
[edit] Poster Presentations
- Mosaik: A reference-guided assembler for next-generation sequence data. Biology of Genomes Meeting, Cold Spring Harbor Laboratory. (May 2007)
- Automatic Somatic Mutation Detection. Biology of Genomes Meeting, Cold Spring Harbor Laboratory. (May 2006)
- Improved SNP Discovery Performance Using Advanced Algorithms. Boston College. (October 2005)
[edit] Publications
- Stromberg, M.P. and Marth, G.T. Mosaik: A reference-guided assembler for next-generation sequence data. Manuscript in preparation (2007).
- Quinlan, A.R, Stewart, D.A., Stromberg, M.P., and Marth, G.T. PYROBAYES: An improved base-calling program for pyrosequences. Manuscript in preparation (2007).
- Quinlan, A.R., Clark, A. G., Fewell, G., Stromberg, M., Mardis, E. R., and G. T. Marth. Whole-genome SNP discovery in ten Drosophila melanogaster lines with light-shotgun 454 pyrosequences. Manuscript in preparation (2007).
- Shih, P., Stromberg, M., Filopei, J. and J.L. Paluh. Checkpoints and Asymmetry: Integrating spindle events with mitotic signaling from metaphase to telophase. Recent Research Developments in Molecular Biology. Invited review in preparation (2007).
- Unneberg, P., Stromberg, M., Lundeberg, J., Jansson, S. & Sterky, F. Analysis of 70,000 EST sequences to study divergence between two closely related Populus species. Tree Genetics & Genomes 1, 109-115 (2005).
- Unneberg, P., Stromberg, M. & Sterky, F. SNP discovery using advanced algorithms and neural networks. Bioinformatics 21, 2528-2530 (2005).
- Stromberg, M. Secure Content Protection: An Overview of the Proposed Security Mechanisms in Digital Cinema. Swedish-Bulgarian Government IT Security Conference Proceedings on Virtual Private Networks and Public Key Infrastructures (2001).
- Lindsey, C.S. & Stromberg, M. Image classification using the frequencies of simple features. Pattern Recognition Letters 21, 265-268 (2000).
